Adam - I think you probably need to provide a little more context for your question. It really depends on the mandate and profile of the portfolio strategy. Are you running intraday, daily or monthly rebalances? Is it driven by fundamental, valuation, momentum, technical or other indicators. Can you adjust your net and gross exposure or are you trying to keep those stable (i.e. replacing positions that have less attractive signals with positions with more attractive signals)?
This questions feels a little like "What are some ideas for profit-making on an equity strategy"? :) There's lots of ideas out there but it really depends on what you're trying to do...