Some of Quantopian styles ,Size and value, are Fama French factors, which are well known to explain a large component of stocks returns. In other words are good predictors, or in the language of quantopian, good alpha factors (to distinguish them from another Frama French variable, market returns, whose correlation with stocks is taken into account by the beta parameter).
I prefer to just call all these variable predictors, which is general terms used in time series analysis.
Momentum and short term reversal are also well know predictors.
Being neutral to them does not mean to have less risk, it just means to be get returns which are no correlated to those predictors (I think called specific returns by quantopian) . The reason is quite simple: who would start a company to re-invent the wheel?
Let's say you found a new alpha factor. If it becomes of public domain, Quantopian could include it in the list of styles, make money on it without informing you, and force everybody to develop new strategies not relying on it. Of course this is an extreme example, but if you were the one who discovered size and value predictors, it could have happened to you.
From the point of view of Quantopian this is a risk management strategy in the sense that investing in many different strategies which are not correlated can be considered an effective risk management approach.
But no alpha factor in itself is more risky than another., and if you were neutral to all possible factors you would juts make no money .. I guess it can be proved mathematically and rigorously.