Low volatility strategies have become more popular among investors in recent years. A topic that may interest the Quantopian community is robust methods for covariance estimation, and would be useful in building a robust minimum variance algorithm for trading. Take a look at Jim Gatheral's paper on using random matrix theory to filter sample covariance matrices. He shows that a minimum variance strategy in equities has stronger performance when using the filtered covariance matrix than the sample covariance or factor-based covariance matrices like Barra's. The motivation for using RMT is to separate a true covariance signal from noise by ascertaining how likely are observed volatilities and correlations to occur in randomly generated data, often with eigenvalue decompositions.